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<blockquote data-quote="ollie989898" data-source="post: 9231668" data-attributes="member: 54866"><p><em>Secondary</em> hypertension can be due to a number of things. Where hypertension is refractory to conventional treatment (i.e. combinations of medicines or therapies), it begins to raise suspicions of something else occurring because we know how most antihypertensive medications work really really well.</p><p></p><p>Signs of secondary hypertension caused by a specific pathology:</p><p></p><p>- Hypertension in a young person, particularly if they are sub 20 years of age- if they haven't aged then they are unlikely to have primary hypertension, surely?</p><p>- Abrupt onset (primary hypertension normally accumulates steadily over many years).</p><p>- Signs of some secondary condition (there are so many of these I couldn't even know where to begin to list them).</p><p>- No family history of hypertension (can be possible, probably unlikely, I don't actually know the details of this).</p><p>- Again, hypertension that doesn't respond to conventional treatments.</p><p></p><p>Potential causes of secondary hypertension</p><p></p><p>Right in at the top- <strong>medicines</strong>. Prescription medicines: steroids, contraceptive pills, hormone replacements and others all too numerous to list. Because drugs have all different effects, one of them might involve a change in blood pressure.</p><p>Not far behind: non-prescription medicines/drugs: alcohol, ecstasy, <strong>cocaine</strong>, nicotine, caffeine- again, these things bind to all sorts of things. If they are the right shape to bind to receptors in the heart- increased heart rate, increased force of contraction= blood pressure goes up.</p><p></p><p>Other causes in no particular order:</p><p></p><p>-Kidney disease, either failure of the kidney or stenosis (narrowing) of the arteries that supply the kidneys, meaning they can't regulate blood volume as well as before. More blood= more filling of the heart= more output of the heart.</p><p></p><p>-Endocrine conditions: Conn's/Cushing's, Acromegaly (excess growth hormone) or overactive thyroid (the thyroid sort of acts like the body's accelerator pedal, you push it, more things happen faster).</p><p></p><p>-Pregnancy- lots of hormones sloshing around (again this is more go pedal), more blood volume= more filling of heart=more heart output so a rise in blood pressure is sort of expected in pregnancy. Also pre-eclampsia in pregnancy.</p><p></p><p><em>Rare as fudge</em>- pheochromocytoma- a tumour in one of the adrenal glands which begins secreting catecholamines (adrenaline etc), so your system is put into maximum fight or flight mode 24/7. Adrenaline binds to all sorts of receptors, including the cardiovascular system making blood pressure increase. I'd imagine you would feel pretty strange if you had one of these, sweating, palpitations, etc.</p><p></p><p>Hope you found this all interesting. Pretty cool this thing you're in control of, innit?</p></blockquote><p></p>
[QUOTE="ollie989898, post: 9231668, member: 54866"] [I]Secondary[/I] hypertension can be due to a number of things. Where hypertension is refractory to conventional treatment (i.e. combinations of medicines or therapies), it begins to raise suspicions of something else occurring because we know how most antihypertensive medications work really really well. Signs of secondary hypertension caused by a specific pathology: - Hypertension in a young person, particularly if they are sub 20 years of age- if they haven't aged then they are unlikely to have primary hypertension, surely? - Abrupt onset (primary hypertension normally accumulates steadily over many years). - Signs of some secondary condition (there are so many of these I couldn't even know where to begin to list them). - No family history of hypertension (can be possible, probably unlikely, I don't actually know the details of this). - Again, hypertension that doesn't respond to conventional treatments. Potential causes of secondary hypertension Right in at the top- [B]medicines[/B]. Prescription medicines: steroids, contraceptive pills, hormone replacements and others all too numerous to list. Because drugs have all different effects, one of them might involve a change in blood pressure. Not far behind: non-prescription medicines/drugs: alcohol, ecstasy, [B]cocaine[/B], nicotine, caffeine- again, these things bind to all sorts of things. If they are the right shape to bind to receptors in the heart- increased heart rate, increased force of contraction= blood pressure goes up. Other causes in no particular order: -Kidney disease, either failure of the kidney or stenosis (narrowing) of the arteries that supply the kidneys, meaning they can't regulate blood volume as well as before. More blood= more filling of the heart= more output of the heart. -Endocrine conditions: Conn's/Cushing's, Acromegaly (excess growth hormone) or overactive thyroid (the thyroid sort of acts like the body's accelerator pedal, you push it, more things happen faster). -Pregnancy- lots of hormones sloshing around (again this is more go pedal), more blood volume= more filling of heart=more heart output so a rise in blood pressure is sort of expected in pregnancy. Also pre-eclampsia in pregnancy. [I]Rare as fudge[/I]- pheochromocytoma- a tumour in one of the adrenal glands which begins secreting catecholamines (adrenaline etc), so your system is put into maximum fight or flight mode 24/7. Adrenaline binds to all sorts of receptors, including the cardiovascular system making blood pressure increase. I'd imagine you would feel pretty strange if you had one of these, sweating, palpitations, etc. Hope you found this all interesting. Pretty cool this thing you're in control of, innit? [/QUOTE]
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